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1

Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors

Stephen E. Webber, Joseph T. Marakovits, Peter S. Dragovich, Thomas J. Prins, Ru Zhou, Shella A. Fuhrman, Amy K. Patick, David A. Matthews, Caroline A. Lee, Babu Srinivasan, Terry Moran, Clifford E. F

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 132 KB

english, 2001

2

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure–Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics

Peter S. Dragovich, Thomas J. Prins, Ru Zhou, Theodore O. Johnson, Edward L. Brown, Fausto C. Maldonado, Shella A. Fuhrman, Leora S. Zalman, Amy K. Patick, David A. Matthews, Xinjun Hou, James W. Mead

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 181 KB

english, 2002

3

Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Peter S Dragovich, Stephen E Webber, Thomas J Prins, Ru Zhou, Joseph T Marakovits, Jayashree G Tikhe, Shella A Fuhrman, Amy K Patick, David A Matthews, Clifford E Ford, Edward L Brown, Susan L Binford

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 336 KB

english, 1999

4

Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

Peter S. Dragovich, Ru Zhou, Stephen E. Webber, Thomas J. Prins, Annette K. Kwok, Koji Okano, Shella A. Fuhrman, Leora S. Zalman, Fausto C. Maldonado, Edward L. Brown, James W. Meador III, Amy K. Pati

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2000

Langue:

english

Fichier:

PDF, 165 KB

english, 2000

5

Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides

Peter S. Dragovich, Ru Zhou, Donald J. Skalitzky, Shella A. Fuhrman, Amy K. Patick, Clifford E. Ford, James W. Meador III, Stephen T. Worland

Journal:

Bioorganic & Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 242 KB

english, 1999

6

Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease

Johnson, Theodore O., Hua, Ye, Luu, Hiep T., Brown, Edward L., Chan, Fora, Chu, Shao Song, Dragovich, Peter S., Eastman, Brian W., Ferre, Rose Ann, Fuhrman, Shella A.

Journal:

Journal of Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 119 KB

english, 2002

7

Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Webber, Stephen E., Tikhe, Jayashree, Worland, Stephen T., Fuhrman, Shella A., Hendrickson, Thomas F., Matthews, David A., Love, Robert A., Patick, Amy K., Meador, James W., Ferre, Rose Ann

Journal:

Journal of Medicinal Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 350 KB

english, 1996

8

An optical thin film assay incorporating rhinovirus protease inhibitors as detector reagents

Anna Ettinger, Rachel Ostroff, Marynette Rhihanek, Peter S Dragovich, Leora S Zalman, Amy K Patick, Thomas J Prins, Shella A Fuhrman, Edward L Brown, Stephen T Worland, Barry Polisky

Journal:

Antiviral Research

Année:

2004

Langue:

english

Fichier:

PDF, 153 KB

english, 2004

9

The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual Function Target for Common Cold Antiviral Therapy

Robert A Love, Karen A Maegley, Xiu Yu, Rose Ann Ferre, Laura K Lingardo, Wade Diehl, Hans E Parge, Peter S Dragovich, Shella A Fuhrman

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2004

10

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics

Dragovich, Peter S., Prins, Thomas J., Zhou, Ru, Fuhrman, Shella A., Patick, Amy K., Matthews, David A., Ford, Clifford E., Meador, James W., Ferre, Rose Ann, Worland, Stephen T.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 136 KB

english, 1999

11

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

Dragovich, Peter S., Prins, Thomas J., Zhou, Ru, Brown, Edward L., Maldonado, Fausto C., Fuhrman, Shella A., Zalman, Leora S., Tuntland, Tove, Lee, Caroline A., Patick, Amy K., Matthews, David A., Hen

Journal:

Journal of Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 255 KB

english, 2002

12

Transcription and processing of intervening sequences in yeast tRNA genes

Knapp, Gayle, Beckmann, Jacques S., Johnson, Peter F., Fuhrman, Shella A., Abelson, John

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 7.27 MB

english, 1978

13

[Part 2: Biological Sciences] || Identification of a RNA Polymerase II Initiation Site in the Long Terminal Repeat of Moloney Murine Leukemia Viral DNA

Shella A. Fuhrman, Charles Van Beveren and Inder M. Verma

Journal:

Proceedings of the National Academy of Sciences

Année:

1981

Langue:

english

Fichier:

PDF, 1.42 MB

english, 1981

14

Adrenocorticotropic hormone stimulation of adrenal RNA polymerase I and III activities. Nucleotide incorporation into internal positions and 3' chain termini

Fuhrman, Shella A., Gill, Gordon N.

Journal:

Année:

1975

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1975

15

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Dragovich, Peter S., Webber, Stephen E., Babine, Robert E., Fuhrman, Shella A., Patick, Amy K., Matthews, David A., Lee, Caroline A., Reich, Siegfried H., Prins, Thomas J., Marakovits, Joseph T., Litt

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 267 KB

english, 1998

16

Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation

Reich, Siegfried H., Johnson, Theodore, Wallace, Michael B., Kephart, Susan E., Fuhrman, Shella A., Worland, Stephen T., Matthews, David A., Hendrickson, Thomas F., Chan, Fora, Meador, James, Ferre, R

Journal:

Journal of Medicinal Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 713 KB

english, 2000

17

Adrenocorticotropic hormone rgulation of adrenal RNA polymerases. Stimulation of nuclear RNA polymerase III

Fuhrman, Shella A., Gill, Gordon N.

Journal:

Année:

1976

Langue:

english

Fichier:

PDF, 958 KB

english, 1976

18

Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements

Webber, Stephen E., Okano, Koji, Little, Thomas L., Reich, Siegfried H., Xin, Yue, Fuhrman, Shella A., Matthews, David A., Love, Robert A., Hendrickson, Thomas F., Patick, Amy K., Meador, James W., Fe

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 411 KB

english, 1998

19

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Dragovich, Peter S., Webber, Stephen E., Babine, Robert E., Fuhrman, Shella A., Patick, Amy K., Matthews, David A., Reich, Siegfried H., Marakovits, Joseph T., Prins, Thomas J., Zhou, Ru, Tikhe, Jayas

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 334 KB

english, 1998

20

Mass spectrometric detection of the noncovalent GDP-bound conformational state of the human H-ras protein

Ganguly, Ashit K., Pramanik, Birendra N., Tsarbopoulos, Anthony, Covey, Thomas R., Huang, Eric, Fuhrman, Shella A.

Journal:

Journal of the American Chemical Society

Année:

1992

Langue:

english

Fichier:

PDF, 914 KB

english, 1992

21

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P 1 Lactam Moieties as l -Glutamine Replacements

Dragovich, Peter S., Prins, Thomas J., Zhou, Ru, Webber, Stephen E., Marakovits, Joseph T., Fuhrman, Shella A., Patick, Amy K., Matthews, David A., Lee, Caroline A., Ford, Clifford E., Burke, Benjamin

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 155 KB

english, 1999

22

Hormonal Control of Adrenal RNA Polymerase Activities*

FUHRMAN, SHELLA A., GILL, GORDON N.

Journal:

Année:

1974

Langue:

english

Fichier:

PDF, 1021 KB

english, 1974